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03 May 2011

Cool Stuff = Nanoparticles

In addition to the ever-elusive, yet-to-be-discovered cures for cancer, AIDS, Alzheimer's, etc. (although there I hear they're not too far away), there is another important world health concern that needs addressing, and it seems to fall on and off the radar for most of us...especially when we're feeling "like a cold's coming on" and just want anything that will zap it.

The prevalent use of antibiotics over the past several decades has an unintended consequence: the emergence of "superbugs", infectious bacteria that have resistance to all available antibiotics on the market -- and there are few, if any, promising drugs in the pipeline.  "Some experts warn health-care provision is in danger of reverting back to a pre-antibiotic era in which hip replacements, care of preterm babies and advanced cancer treatment are no longer possible."

But, check it out!
IBM researchers created a new type of nanoparticles that are capable of destroying the membrane walls of certain drug-resistant bacteria strains, leaving the cells to harmlessly degrade without any trace. The new system works by using biodegradable plastic to engineer electrically charged nanoparticles that in turn attract to the bacteria’s opposite charge, in turn destroying the membrane walls hence the cell entirely.


Of course there are many more questions to consider regarding manufacturing of a nanoparticle type of drug (What would the dosage form be? How expensive is it to produce? etc), but I read these findings and just think "man, science is cool."

2 comments:

  1. How prevalent are these super bugs? I mean, I imagine that there are quite a few that are resistant to one or two antibiotics, but how many are resistant to ALL? Time to break out the Primaxin, OTC version! haha

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  2. I actually saw a movie about future technology. One of the ideas that is estimated to hit the market in the future (probably many years from now) was nanoparticle cells in your body that can download software to change shape to specific antibodies that could attack bugs in your bloodstream. Thought that was pretty cool. The movie was called "The Singularity" in case you are interested.

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